Publications by authors named "C Carlsten"

Introduction: Persistent lung abnormalities following COVID-19 infection are common. Similar parenchymal changes are observed in idiopathic pulmonary fibrosis (IPF). We investigated whether common genetic risk factors in IPF are associated with developing lung parenchymal abnormalities following severe COVID-19 disease.

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Background: Mounting evidence links exposure to traffic-related air pollution (TRAP) to impairment in cognitive functioning.

Objectives: To determine if short-term, controlled exposure to diesel exhaust (DE) adversely affects one or more cognitive function domains.

Methods: We carried out a double-blinded crossover design with 28 healthy, adult volunteers.

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Article Synopsis
  • The study investigates the relationship between exposure to outdoor air pollutants and the development of asthma in adults, with a focus on pollutants such as particulate matter (PM), nitrogen dioxide (NO), ozone (O), and sulfur dioxide (SO).
  • After reviewing 1,891 references and narrowing it down to 25 relevant studies, the meta-analysis found that higher levels of PM and NO were associated with an increased risk of developing asthma in adults, while ozone did not show a significant association.
  • The results revealed a pooled relative risk of 1.07 for PM and 1.11 for NO, indicating that as exposure to these pollutants rises, so does the likelihood of new-onset asthma, although there was considerable
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Ortho-phthalates (herein referred to as phthalates) are synthetic chemicals used in thousands of different everyday products and materials. Nearly ubiquitous environmental exposure is reflected by phthalate metabolites in the urine of almost all Canadians. However, phthalate exposure tends to be higher amongst people of low socioeconomic status and ethnic minorities.

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Article Synopsis
  • Vancouver Coastal Health (VCH) Authority in British Columbia serves both urban and rural areas, making it a unique case for studying care services for asthma and chronic obstructive pulmonary disease (COPD).
  • An environmental scan revealed that specialized care services for asthma and COPD are limited in urban areas and largely unavailable in rural areas, with spirometry services falling significantly short of needs in both regions.
  • None of the 16 identified quality improvement (QI) initiatives for asthma and COPD were conducted in rural VCH healthcare sites, indicating a significant gap in care accessibility and a need for targeted future QI initiatives in those communities.
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