Background: Adverse events induced by intravesical bacillus Calmette-Guérin (BCG) to treat high-grade non-muscle-invasive bladder cancer (NMIBC) often lead to treatment discontinuation. The EAU-RF NIMBUS trial found a reduced number of standard-dose BCG instillations to be inferior with the standard regimen. Nonetheless, it remains important to evaluate whether patients in the reduced BCG treatment arm had better quality of life (QoL) due to a possible reduction in toxicity or burden.
View Article and Find Full Text PDFInt J Parasitol Parasites Wildl
December 2021
In early September 2019, a morbidity and mortality event affecting California tiger salamanders () and Santa Cruz long-toed salamanders () in late stages of metamorphosis was reported at a National Wildlife Refuge in Santa Cruz County, California, U.S.A.
View Article and Find Full Text PDFJ Urol
April 2021
Purpose: We evaluated unmet needs of lower urinary tract symptoms-benign prostatic enlargement pharmacological treatment by measuring symptom improvement, persistence and deterioration in real life. A prospective registry was conducted for 24 months in 5 European countries and analyzed by the European Association of Urology Research Foundation.
Materials And Methods: Previously untreated and treated patients were enrolled to the registry in both primary care and urology referral centers in France, Germany, Italy, Spain and the UK.