Introduction: The Pregnancy and Newborn Diagnostic Assessment (PANDA) system is a mobile application designed to facilitate diagnosis and decision-making by healthcare staff in antenatal care (ANC). This study aimed to evaluate its effectiveness in improving the quality of ANC.
Methods: This randomised controlled trial implemented the PANDA system in two groups of health facilities (intervention and comparison groups) using a matched-pair method in the Koupéla health district, Burkina Faso.
The authors share experiences of a global health partnership that worked to promote equity through a commitment to shared values and goals, engagement and communication, and mutual trust and respect.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
August 2023
Central nervous system (CNS) involvement in childhood-onset systemic lupus erythematosus (cSLE) occurs in more than 50% of patients. Structural magnetic resonance imaging (MRI) has identified global cerebral atrophy, as well as the involvement of the corpus callosum and hippocampus, which is associated with cognitive impairment. In this cross-sectional study we included 71 cSLE (mean age 24.
View Article and Find Full Text PDFIntroduction: Hydrogen sulfide (HS) is a fundamental biological endogenous gas-mediator in the respiratory system. It regulates pivotal patho-physiological processes such as oxidative stress, pulmonary circulation, airway tone and inflammation.
Objectives: We herein describe the design and synthesis of molecular hybrids obtained by the condensation of several corticosteroids with different hydrogen sulfide releasing moieties.