Publications by authors named "C Campoli"
(1) Background: The impact of inflammation on voriconazole exposure in oncohematological pediatric patients represents a debated issue. We aimed to investigate the impact of serum C-reactive protein (CRP), procalcitonin (PCT), and interleukin-6 (IL-6) levels on voriconazole exposure in oncohematological pediatric patients requiring allogeneic hematopoietic stem cell transplantation (HCT). (2) Methods: Pediatric patients undergoing allogeneic HCT and receiving therapeutic drug monitoring (TDM)-guided voriconazole as primary antifungal prophylaxis between January 2021 and December 2023 were included.
View Article and Find Full Text PDFMollaret's meningitis is a rare neurological disorder characterized by recurrent episodes of aseptic lymphocytic meningitis, often associated with herpes simplex virus 2 (HSV-2) infection. We report the case of a 39 y.o.
View Article and Find Full Text PDFThe cuticle covering aerial organs of land plants is well known to protect against desiccation. Cuticles also play diverse and specialized functions, including organ separation, depending on plant and tissue. Barley shows a distinctive cuticular wax bloom enriched in β-diketones on leaf sheaths, stem nodes and internodes and inflorescences.
View Article and Find Full Text PDFArticle Synopsis
- Visceral leishmaniasis (VL) is a serious disease increasingly seen in northern Italy, especially in children and those with weakened immune systems.
- A study at St. Orsola University Hospital analyzed 16 hospitalized children over nine years, revealing that most presented with fever, low blood cell counts, and swollen spleens; treatments with Liposomal Amphotericin B effectively managed symptoms.
- Pediatricians should consider VL as a potential diagnosis for children with unexplained fever and related symptoms, using abdominal ultrasounds and blood tests for diagnosis instead of invasive procedures like bone marrow aspiration.
Article Synopsis
- The study examined the effectiveness of three antiviral treatments for early COVID-19 (nirmatrelvir/ritonavir, molnupiravir, and remdesivir) among a large group of outpatient patients.
- 1,342 patients were analyzed, with high clinical recovery rates (96.9%) and a low hospitalization rate (2.6%), showing no significant differences in outcomes between the antiviral treatments.
- Vaccination status was important, as vaccinated patients had a lower risk of hospitalization or death compared to unvaccinated individuals.