Publications by authors named "C COLLAZOS"
Multimeric aptamers have gained more attention than their monomeric counterparts due to providing more binding sites for target analytes, leading to increased affinity. This work attempted to engineer the surface-based generation of multimeric aptamers by employing the room temperature rolling circle amplification (RCA) technique and chemically modified primers for developing a highly sensitive and selective electrochemical aptasensor. The multimeric aptamers, generated through surface RCA, are hybridized to modified spacer primers, facilitating the positioning of the aptamers in the proximity of sensing surfaces.
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- Hepatitis B infection is widespread in China, and researchers aimed to evaluate the awareness of its transmission among Chinese patients and their household contacts in comparison to non-Chinese individuals.
- A total of 182 patients and 398 contacts participated in interviews about their knowledge of HBV transmission, with many Chinese participants reporting language barriers.
- Results showed that Chinese patients had better awareness of vertical transmission and used preventive measures more effectively, though vaccination rates were slightly lower among their household contacts compared to controls.
Drug-induced liver injury (DILI) is a challenging liver disorder for hepatologists. We aimed to assess the pattern and causes of DILI in a tertiary hospital. We registered prospectively all patients referred with suspicion of DILI from 2018 to 2023.
View Article and Find Full Text PDFDiagnosing dengue in endemic areas remains problematic because of the low specificity of the symptoms and lack of accurate diagnostic tests. This study aimed to develop and prospectively validate, under routine care, dengue diagnostic clinical algorithms. The study was carried out in two phases.
View Article and Find Full Text PDFObjectives: The aim of this work is to provide a scoping review to compile and classify the systems helping train and enhance psychomotor skills in hearing impaired (HI) children.
Methods: Based on an exhaustive review on psychomotor deficits in HI children, the procedure used to carry out a scoping review was: select keywords and identify synonyms, select databases and prepare the queries using keywords, analyze the quality of the works found using the PEDro Scale, classify the works based on psychomotor competences, analyze the interactive systems (e.g.