Publications by authors named "C C Su Mon"
Non-high-risk (non-HR) neuroblastoma (NB) patients have excellent outcomes, with more than a 90% survival rate, whereas HR NB patients expect less than a 50% survival rate. Metastatic disease is the principal cause of death among both non-HR and HR NB patients. Previous studies have reported the significant but limited prognostic value of quantitative PCR (qPCR)-based assays, measuring overlapping but different sets of neuroblastoma-associated mRNAs (NB-mRNAs), to detect metastatic disease in both non-HR and HR patient samples.
View Article and Find Full Text PDFArticle Synopsis
- Bleomycin-induced lung injury leads to inflammation and fibrosis, similar to conditions like idiopathic pulmonary fibrosis, and stem cell therapy is being explored as a treatment option.
- Multilineage-differentiating stress-enduring (Muse) cells, which are stem cells found in various tissues, can target and repair damaged lung tissue without the need for immunosuppressants.
- In a rat study, those treated with Muse cells from preterm and term umbilical cords showed significant improvements in recovery metrics such as weight, serum levels, and lung injury scores compared to controls.
Background: Genetic causes are increasingly recognized in patients with focal segmental glomerulosclerosis (FSGS), but it remains unclear which patients should undergo genetic study. Our objective was to determine the frequency and distribution of genetic variants in steroid-resistant nephrotic syndrome FSGS (SRNS-FSGS) and in FSGS of undetermined cause (FSGS-UC).
Methods: We performed targeted exome sequencing of 84 genes associated with glomerulopathy in patients with adult-onset SRNS-FSGS or FSGS-UC after ruling out secondary causes.
Article Synopsis
- * Typically, MRD is evaluated more effectively in BM than in PB, but this case highlights a 3-year-old girl with HR-NB who had unexpectedly higher PB-MRD levels compared to BM-MRD prior to her relapses.
- * Despite initially achieving complete remission through standard treatment, the patient experienced two relapses, with monitoring showing that PB-MRD levels increased remarkably before each relapse, suggesting that PB-MRD could be a significant indicator for evaluating
Background: The role of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in the management glomerular/systemic autoimmune diseases with proteinuria in real-world clinical settings is unclear.
Methods: This is a retrospective, observational, international cohort study. Adult patients with biopsy-proven glomerular diseases were included.