Background: COVID-19 mRNA vaccines have demonstrated 95 % efficacy in the general population. However, their immunogenicity in adolescents with Type 1 Diabetes (T1D), who exhibit weaken immune responses, remains insufficiently explored.
Methods: Longitudinal analysis of innate immune responses following PRR-agonists and BNT162b2 vaccine stimulations, along with S-specific antibody responses, memory T cell recall responses, and RNA-sequencing were assessed in eight T1D adolescents and 16 healthy controls at six different timepoints.
Chlorogenic acid, a well-known antioxidant, has potential applications in health care, food, and cosmetic sectors. However, its low solubility hinders its application at the industrial scale. The primary goal of the present study was to increase the lipophilic property of chlorogenic acid through esterification using an ultrasonication approach and Novozym® 435 as the catalyst.
View Article and Find Full Text PDFThe 5A's Framework (Assess, Advise, Assist, Agree, and Arrange) has been recommended as a practice guide for obesity counseling. Its integration in research, however, is not well known. This systematic review was to find how the 5A's Framework was integrated in research on obesity and weight counseling.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Purpose: To compare deep learning (DL)-based and conventional reconstruction through subjective and objective analysis and ascertain whether DL-based reconstruction improves the quality and acquisition speed of clinical abdominal magnetic resonance imaging (MRI).
Methods: The 124 patients who underwent abdominal MRI between January and July 2021 were retrospectively studied. For each patient, two-dimensional axial T-weighted single-shot fast spin-echo MRI images with or without fat saturation were reconstructed using DL-based and conventional methods.