Pseudoplacentational endometrial hyperplasia (PEH) and cystic endometrial hyperplasia (CEH) are both hyperplastic conditions that may occur in the canine uterus during diestrus. CEH can impair fertility, and, although the consequences of PEH are poorly known, this condition is significantly associated with pyometra. The aim of this study was to investigate frequencies of both PEH and CEH in female dogs according to age, size, breed, and breed group.
View Article and Find Full Text PDFCopy-number variants (CNVs) are an important class of genetic variation that can mediate rapid adaptive evolution. Whereas CNVs can increase the relative fitness of the organism, they can also incur a cost due to the associated increased gene expression and repetitive DNA. We previously evolved populations of Saccharomyces cerevisiae over hundreds of generations in glutamine-limited (Gln-) chemostats and observed the recurrent evolution of CNVs at the GAP1 locus.
View Article and Find Full Text PDFObjective: To compare the vocal symptomatology of professors from a federal university who engaged in distance, hybrid, and face-to-face teaching during and after the Coronavirus Disease 2019 (COVID-19) pandemic period.
Method: The study included 40 university professors, 20 men and 20 women, whose symptomatology was monitored at three time points: during the distance teaching period due to social isolation caused by COVID-19, in hybrid teaching (partial return), and upon returning to face-to-face teaching, which required the use of face masks and posed contamination risks.
Results: The hybrid phase presented the highest absence of vocal complaints/discomfort, and most participants did not need to be reassigned due to vocal problems.
Aim: To assess for the first time the safety and feasibility of combining photon-IntraOperative RadioTherapy (ph-IORT) with hypofractionated whole-breast irradiation (hWBI) in patients referred to adjuvant radiotherapy after Breast-Conserving Surgery (BCS).
Methods: From February 2019 to August 2020, patients referred for breast-conserving surgery (BCS) in our institution were prospectively included in the present trial. BCS was discussed in the multidisciplinary tumor board (MTB).