Publications by authors named "C C Patrick"
Study Objective: To evaluate the comparative effectiveness of fentanyl and ketamine via Breath Actuated Nebulizer (BAN) for analgesia in the prehospital setting.
Methods: We conducted a retrospective cross-sectional evaluation of patients receiving fentanyl or ketamine via BAN for pain management in a large suburban EMS system between 3/1/2022 and 6/1/2023. The primary outcome was change in first to last pain score.
Prior studies have found an association between reduced P3 brain responses-a neural marker of task engagement-and increased depressive symptoms during adolescence. However, it is unclear whether P3 correlates with depression globally, or with certain facets. Existing depression studies have also typically quantified P3 as a cross-trial average, neglecting possible trial-by-trial effects.
View Article and Find Full Text PDFPurpose: In thyroid eye disease (TED), activation and proliferation of orbital fibroblasts (OFs) promotes remodeling and causes an increase in the volume of orbital tissue. Platelet-derived growth factors (PDGFs) are elevated in TED and promote OF activation. The aryl hydrocarbon receptor (AHR), a ligand activated nuclear receptor, is important in regulating OF activation.
View Article and Find Full Text PDFObjectives: To evaluate the motor proficiency, identify risk factors for abnormal motor scores, and examine the relationship between motor proficiency and health-related quality of life in school-aged patients with CHD.
Study Design: Patients ≥ 4 years old referred to the cardiac neurodevelopmental program between June 2017 and April 2020 were included. Motor skills were evaluated by therapist-administered and parent-reported and questionnaires.
Article Synopsis
- Psychophysiology can provide insights into the structure and development of psychopathology, with a focus on the P300 component as a marker for genetic risk related to externalizing behaviors.
- The study utilized data from the Minnesota Twin Family Study and found that blunted P300 at age 14 was linked to higher risk of broader externalizing behaviors at age 17, rather than specific syndromes.
- Results highlight the benefit of using a HiTOP framework and various measurement methods to better understand the development of mental health issues over time.