Implementability of opioid deprescribing interventions at transitions of care: A scoping review.

Continuation of opioids at transitions of care increases the risk of long-term opioid use and related harm. To our knowledge, no study has examined the implementability of opioid deprescribing interventions at transitions of care. Our scoping review aimed to identify the type of opioid deprescribing interventions employed at transitions of care and assess the implementability of tested interventions.

Corticospinal and Clinical Effects of Muscle Tendon Vibration in Neurologically Impaired Individuals. A Scoping Review.

This review verified the extent, variety, quality and main findings of studies that have tested the neurophysiological and clinical effects of muscle tendon vibration (VIB) in individuals with sensorimotor impairments. The search was conducted on PubMed, CINAHL, and SportDiscuss up to April 2024. Studies were selected if they included humans with neurological impairments, applied VIB and used at least one measure of corticospinal excitability using transcranial magnetic stimulation (TMS).

Limbic system synaptic dysfunctions associated with prion disease onset.

Misfolding of normal prion protein (PrP) to pathological isoforms (prions) causes prion diseases (PrDs) with clinical manifestations including cognitive decline and mood-related behavioral changes. Cognition and mood are linked to the neurophysiology of the limbic system. Little is known about how the disease affects the synaptic activity in brain parts associated with this system.

Predicting the replicability of social and behavioural science claims in COVID-19 preprints.

Replications are important for assessing the reliability of published findings. However, they are costly, and it is infeasible to replicate everything. Accurate, fast, lower-cost alternatives such as eliciting predictions could accelerate assessment for rapid policy implementation in a crisis and help guide a more efficient allocation of scarce replication resources.

A pair of two atrial myxomas mimic thrombus in left atrial appendage and cause ischemic stroke in a young adult: a case report.

Background: Stroke is one of the leading causes of mortality and disability and can be rarely caused by cardiac myxoma.

Case Summary: Here, we report about a 56-year-old man who suffered from a stroke presented with acute dysarthria and left hemiparesis. Magnetic resonance imaging (MRI) of the brain revealed an acute stroke.