Publications by authors named "C C Goulart"
Impact of Respiratory Support During Hospitalization on Functional Outcomes in Long COVID: A Post-Hoc Analysis of a Prospective Cohort Study.
Int J Environ Res Public Health
December 2024
Post-acute COVID-19 syndrome (PACS) is characterized by the persistence of one or more symptoms after the acute phase, leading to physical disabilities. This study aims to investigate whether the functional capacity and respiratory function 120 days post-COVID-19 differed according to the level of respiratory support needed during hospitalization in acute COVID-19 in the pre-vaccine rollout period. We followed up with 118 COVID-19 hospitalized patients in the acute phase until 120 days post-acute disease, with patients split into a Non-Invasive Oxygen Therapy Group (OTG, n = 72), Invasive Mechanical Ventilation Group (IMV, n = 12), and Room Air Group (RAG, n = 34), assessing the body composition, respiratory muscle strength, pulmonary function, functional capacity, and muscle strength at the follow-up visit.
View Article and Find Full Text PDFBackground: In SARS-CoV-2 infection, cytokines and laboratory biomarkers play a key role in disease progression and their long-term levels have been associated with the outcome of long COVID-19.
Objectives: I) study the levels of cytokines, hematological and biochemical biomarkers in the acute and post-acute phases of COVID-19 disease; and II) assess the impact of COVID-19 vaccine doses on fatigue symptoms.
Methods: This study is an exploratory cohort nested within a clinical and laboratory follow-up of surviving participants after pre-vaccine acute COVID-19 infection with severe clinical manifestations.
Article Synopsis
- Heart failure (HF) causes severe breathlessness and fatigue, which can reduce exercise capacity, possibly due to issues in blood flow, muscle strength, and microvascular density.
- This study aimed to examine how adding myofascial release techniques (MRT) to circuit resistance training (CRT) impacts exercise tolerance, muscle strength, quality of life, and depression in HF patients compared to home-based rehabilitation.
- Results showed that after 12 weeks, only the CRT group significantly improved in various exercise tolerance measures and quality of life compared to the unsupervised rehabilitation group, highlighting the effectiveness of structured exercise programs for HF patients.
Article Synopsis
- - The COVID-19 pandemic significantly disrupted pulmonary rehabilitation (PR), necessitating changes in how it is delivered to ensure patient care and outcomes are maintained.
- - A review of studies from various medical databases revealed that multidisciplinary and individualized rehabilitation programs, including telerehabilitation, have shown promise, but many patients still face barriers to access.
- - Despite effective treatment options, the uptake of PR remains low globally, especially in low-income countries where technological limitations hinder service delivery.