Publications by authors named "C C Gluer"

Backgroud: Hypoparathyroidism (hypoPT) is characterized by acute and chronic complications due to insufficient parathyroid hormone (PTH) production or action. Several management guidelines have been developed, but mostly based on evidence from Western countries. Data from Eastern countries have not been systematically compared with those from Western countries.

View Article and Find Full Text PDF

Osteoporosis is underdiagnosed and undertreated. To improve timely fracture risk assessment optimized densitometry methods are required such as opportunistic spinal quantitative computed tomography (QCT). However, it is unclear how to best calibrate these scans and correct for potential scanner drift of QCT when used for monitoring bone mineral density (BMD) changes.

View Article and Find Full Text PDF

The immune system plays an important role in fracture healing, by modulating the pro-inflammatory and anti-inflammatory responses occurring instantly upon injury. An imbalance in these responses can lead to adverse outcomes, such as non-union of fractures. Implants are used to support and stabilize complex fractures.

View Article and Find Full Text PDF
Article Synopsis
  • Osteoporotic fractures pose a significant risk for older adults, yet safe treatments are often underutilized among those most at risk, highlighting the need for better assessment methods.
  • * Artificial intelligence (AI) and machine learning (ML) can improve the identification of individuals at high fracture risk by analyzing complex data from medical records and devices.
  • * While AI-ML has the potential to enhance osteoporosis management through personalized approaches, it's essential to address concerns like model explainability, biases, and the overall impact on clinical practice.
View Article and Find Full Text PDF

Purpose: We developed and tested a neural network for automated detection and stability analysis of vertebral body fractures on computed tomography (CT).

Materials And Methods: 257 patients who underwent CT were included in this Institutional Review Board (IRB) approved study. 463 fractured and 1883 non-fractured vertebral bodies were included, with 190 fractures unstable.

View Article and Find Full Text PDF