Publications by authors named "C C Frear"

Background: Acute application of adjunctive negative pressure wound therapy (NPWT) significantly improves time to re-epithelialization in pediatric burn patients. This adjunctive treatment has not yet been broadly or routinely adopted as a standard primary burns dressing strategy. The Implementation of Negative PRessurE for acute Pediatric burns (INPREP) trial will implement and evaluate the impact of adjunctive NPWT in parallel with co-designed implementation strategies and resources across four major pediatric hospitals.

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Article Synopsis
  • Pediatric burn injuries are a significant healthcare challenge, and while negative pressure wound therapy can enhance healing in children, its use is not uniformly adopted in treatment.
  • The study explored barriers to implementing this therapy in Australian pediatric hospitals through a survey of healthcare professionals and interviews with senior clinicians, identifying eight key obstacles related to resources, knowledge, patient needs, and more.
  • The findings will support the development of targeted strategies and inform future research, emphasizing the need for improved resources, training, and policies to enhance therapy uptake.
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Article Synopsis
  • Delirium is a common and serious complication in hospitalized patients with acute burns, significantly impacting patient outcomes and healthcare systems.
  • A systematic review and meta-analysis identified key risk factors for delirium, including higher ASA scores, larger burn areas, and increased lengths of hospital and ICU stays, although these findings vary in certainty.
  • The study highlights the need for more targeted research to better understand and mitigate delirium in at-risk burn patients during their hospital care.
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Negative pressure wound therapy (NPWT) has been shown to improve clinical outcomes for children with burns by accelerating wound re-epithelialisation. Its effects on healthcare costs, however, remain poorly understood. The aim of this study was to evaluate the cost-effectiveness of NPWT from a healthcare provider perspective using evidence from the SONATA in C randomised controlled trial, in which 101 children with small-area burns were allocated to either standard care (silver-impregnated dressings) or standard care in combination with adjunctive NPWT.

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Background: Stereophotogrammetry (SPG) provides a more objective measurement of burn wound area than traditional clinical assessments. The recently developed Intel® RealSense™ D415/Wound Measure SPG system has yet to undergo formal evaluation in a paediatric population.

Methods: A pilot study comparing the Intel® RealSense™ D415/Wound Measure to the previously validated LifeVizII®/DermaPix® SPG system, for burn assessment was conducted at a tertiary paediatric burn centre.

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