Publications by authors named "C C F Parolo"
Objectives: The objective of this study was to evaluate the feasibility of point-of-care testing (POCT) devices for N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurement in prehospital settings, with the aim of improving the speed and accuracy of stroke diagnosis, thereby facilitating quicker and more effective patient care.
Methods: Prehospital blood samples were collected from suspected stroke patients, and NT-proBNP levels were measured using a POCT device in ambulances and hospitals. Results from the NT-proBNP POCT and smartphone images were analyzed.
Helminthiases are highly prevalent but neglected infections that affect more than 1·5 billion people worldwide. Considering the worldwide prevalence of helminthiases, WHO has declared them a public health concern since 2001, necessitating rigorous control and elimination efforts. However, only a few reliable point-of-care diagnostic tests are available for assessing the effectiveness of public health interventions targeting helminthiases, thus increasing the risk of suboptimal outcomes, misallocation of resources, and emergence of drug-resistant helminths.
View Article and Find Full Text PDFOral microbiota: Taxonomic composition and functional profile in caries-free and in caries-affected individuals - A systematic review.
Arch Oral Biol
December 2024
Objective: To compare the oral microbiota among caries-free (CF) with caries-affected (CA) individuals, both at taxonomic and at functional levels.
Design: This systematic review was conducted following PRISMA guidelines. A structured search was carried out in MEDLINE/PUBMED, Web of Science, EMBASE, LILACS, SciELO, Scopus and Google Scholar databases up to September, 2023.
Article Synopsis
- The study investigates the effectiveness of a modified severe malaria classification for patients in non-endemic areas, as the current WHO definition may misclassify cases.
- Among 506 malaria patients, 34.8% were classified with severe malaria, with only 7.3% developing life-threatening conditions, primarily in the very severe malaria group.
- The findings suggest that existing severity criteria need reevaluation in non-endemic settings, as less severe malaria cases show a low risk of severe outcomes.