Genome-wide microsatellite characterization and their marker development and transferability in Broussonetia Species.

Background: Broussonetia papyrifera, B. monoica, and B. kaempferi belong to the genus Broussonetia (Moraceae).

Hearing Loss as a Risk Factor for Dementia: A Nationwide 15-Year Follow-Up Cohort Study in Taiwan.

Introduction: Although hearing loss is associated with dementia, the exact causal relationship between hearing loss and dementia remains unclear. Early detection and prevention of hearing loss are essential. In this study, data from the National Health Insurance Research Database (NHIRD) of Taiwan were used to monitor patients with hearing loss for 15 years to determine whether hearing loss leads to dementia.

Paternal Cyanidin-3-O-Glucoside Diet Improved High-Fat, High-Fructose Diet-Induced Intergenerational Inheritance in Male Offspring's Susceptibility to High-Fat Diet-Induced Testicular and Sperm Damage.

High-fructose and high-fat diet (HFHFD) has been associated with impaired spermatogenesis, leading to decreased sperm quality and increased male infertility, with similar effects observed in offspring. Cyanidin-3-O-glucoside (C3G), a recognized food antioxidant, has shown promise in protecting in male reproduction and modulating epigenetic modifications. However, its potential role in ameliorating intergenerational inheritance induced by HFHFD remains underexplored.

AA-Stacked Hydrogen-Substituted Graphdiyne for Enhanced Lithium Storage.

Graphdiyne (GDY) has been considered a promising electrode material for application in electrochemical energy storage. However, studies on GDY featuring an ordered interlayer stacking are lacking, which is supposed to be another effective way to increase lithium binding sites and diffusion pathways. Herein, we synthesized a hydrogen-substituted GDY (HsGDY) with a highly-ordered AA-stacking structure via a facile alcohol-thermal method.

A real-world study to evaluate effectiveness of mepolizumab in treating severe asthma in Taiwan (REMIT).

Background: REMIT is the first real-world study of mepolizumab effectiveness in patients with severe asthma (SA) in Taiwan.

Objectives: The primary objective evaluated changes in clinically significant exacerbations (CSEs; defined as use of oral corticosteroids (OCS) or emergency department (ED) visits and/or hospitalizations) in the 12 months pre- and post-mepolizumab treatment. Secondary objectives assessed changes in the number of CSEs requiring ED visits/hospitalizations and daily maintenance OCS (mOCS) dosage 12 months pre- and post-mepolizumab treatment.