Publications by authors named "C C Eschen"

The initial evaluation of stenosis during coronary angiography is typically performed by visual assessment. Visual assessment has limited accuracy compared to fractional flow reserve and quantitative coronary angiography, which are more time-consuming and costly. Applying deep learning might yield a faster and more accurate stenosis assessment.

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  • A study in Denmark focused on patients with COVID-19 associated ARDS who were supported with veno-venous extracorporeal membrane oxygenation (V-V ECMO) to analyze patient selection and outcomes.
  • Out of 1,836 ICU patients, 118 were eligible for ECMO, and 71 were cannulated; the median age of patients was 55, with a 90-day mortality rate of 43%.
  • Findings indicated that being 60 years or older increased mortality risk while pre-existing hypertension reduced it, aligning with outcomes from similar studies.
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Background: Prone position ventilation (PPV) is recommended for patients with COVID-19 induced severe Adult Respiratory Distress Syndrome (ARDS) and is used for patients supported with V-V ECMO as well. The purpose of this study was to describe the use of PPV in these patients focusing on physiological effects with the hypothesis that PPV could reduce oxygen need and improve dynamic compliance.

Methods: This study was a nationwide retrospective analysis of all COVID-19 patients in Denmark from March 2020 - December 2021 with severe ARDS and need of V-V ECMO support.

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Introduction: Prone position ventilation (PPV) of patients with adult respiratory distress syndrome (ARDS) supported with veno-venous extracorporeal membrane oxygenation (V-V ECMO) may improve oxygenation and alveolar recruitment and is recommended when extensive dorsal consolidations are present, but only few data regarding adverse events (AE) related to PPV in this group of patients have been published.

Methods: Nationwide retrospective analysis of 68 COVID-19 patients admitted from March 2020 - December 2021 with severe ARDS and need of V-V ECMO support. The number of patients treated with PPV, number of PPV-events, timing, the time spent in prone position, number and causes of AE are reported.

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  • - The GODIF trial investigates whether using furosemide to remove excess fluid in ICU patients improves outcomes compared to a placebo, as fluid overload is linked to higher mortality in these patients.
  • - Involving 1000 stable adult ICU patients, the trial employs a randomized, blinded, and pragmatic design to measure the primary outcome of days alive and out of the hospital within 90 days after treatment.
  • - The statistical analysis plan includes rigorous methods for comparing treatment groups and considers various prognostic variables to enhance the reliability of the findings regarding furosemide's effectiveness.
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