Publications by authors named "C C Duke"
Article Synopsis
- Exposure to adverse environmental conditions, like extreme heat and high air pollution, is linked to higher stillbirth rates, especially when considering social vulnerability at the county level in the U.S.
- The study used various nationwide datasets to analyze county-level stillbirth rates, environmental factors, and social vulnerability, employing statistical models to identify correlations.
- Results indicated a positive relationship between social vulnerability and stillbirth rates, as well as with extreme heat and fine particulate matter levels, suggesting that communities facing social challenges may be more affected by environmental risks.
GM1-gangliosidosis (GM1) is a lysosomal storage disorder caused by mutations in the galactosidase beta 1 gene () that leads to reduced β-galactosidase (β-gal) activity. This enzyme deficiency results in neuronal degeneration, developmental delay, and early death. A sensitive assay for the measurement of β-gal enzyme activity is required for the development of disease-modifying therapies.
View Article and Find Full Text PDFObjectives: To describe the population pharmacokinetics of cefazolin in infected hospitalized patients requiring intermittent haemodialysis (IHD).
Methods: This prospective population pharmacokinetic study was conducted in IHD patients prescribed cefazolin 2 g three times weekly. Plasma samples were collected at prespecified timepoints and assayed for total and unbound concentrations using validated LC.
In Victoria, Australia, culturally and linguistically diverse communities are more than twice as likely to drown than their Australian-born counterparts. One explanation is the lack of feasible, community-led approaches to water safety and swimming education. A community engagement framework was used to develop and implement a 5-day pool program to teach swimming and water safety to newly arrived migrant children attending an English language school in Victoria.
View Article and Find Full Text PDFObjectives: Black and Hispanic/Latinx individuals experience a greater burden of mental health symptoms as compared to White individuals in the general population. Examination of ethnoracial disparities and mechanisms explaining these disparities among veterans is still in its nascence. The current study examined perceived everyday discrimination and income as parallel mediators of the association between race/ethnicity and PTSD, depression, and general anxiety symptoms in a sample of White, Black, and Hispanic/Latinx veterans stratified by gender.
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