Publications by authors named "C C Dodd"
Purpose: To describe the development of INSIGHT, a real-world data quality tool to assess completeness, consistency, and fitness-for-purpose of observational health data sources.
Methods: We designed a three-level pipeline with data quality assessments (DQAs) to be performed in ConcePTION Common Data Model (CDM) instances. The pipeline has been coded using R.
Article Synopsis
- The study compares the accuracy of experienced surgeons and a machine learning model (ResNet50v2) in predicting patient outcomes from knee replacement radiographs.
- The model performed better than the surgeons, identifying 71% of patients with poor outcomes and 82% with excellent outcomes, while the surgeons struggled significantly.
- The findings suggest that there are specific radiographical features linked to poor outcomes that surgeons may not recognize, indicating a need for further research to improve surgical techniques and patient results.
Article Synopsis
- Preeclampsia (PE) is linked to hypertension and immune responses during pregnancy, with COVID-19 history potentially increasing PE-like symptoms and cognitive issues in affected individuals.
- * Researchers isolated CD4+ T cells from women with PE and those without (some with COVID-19 history) and injected them into pregnant rats to study their impact on blood pressure and cognitive function.
- * The study found that PE, particularly with a COVID-19 history, caused higher blood pressure and cognitive dysfunction in recipient rats, suggesting a significant role of CD4+ T cells in these pregnancy complications.
Comorbidity between post-traumatic stress disorder (PTSD) and substance use disorder may be explained by a prospective trauma risk conferred by both conditions. The current study modeled concurrent and prospective associations of trauma, PTSD symptoms, and substance use (SU) behavior among trauma exposed youth (ages 8-20). Clinical interviews assessed trauma exposure, PTSD symptom severity, and SU behavior at baseline and at six- and 12-month follow up study visits (N = 2,069).
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