Diabetic Serum Inhibits Osteoblast Adhesion to Titanium Surface Through Advanced Glycation End Products: An In Vitro Study.

Purpose: Diabetes mellitus has been shown to delay osseointegration of titanium dental implants. This study tested the hypothesis that serum derived from diabetes negatively affects osteoblast adhesion to polystyrene and titanium surfaces, partly through the presence of advanced glycation end products (AGEs).

Materials And Methods: Twenty-four Sprague-Dawley rats were divided into three groups: normoglycemic control, streptozotocin-induced diabetic group, and diabetic group treated with the AGE inhibitor aminoguanidine.

Use of preexisting radiographs for assessing periodontal disease in epidemiologic studies.

Objectives: This study evaluates the feasibility of obtaining preexisting dental radiographs by mail, the validity of assessing alveolar bone loss from posterior radiographs compared to full mouth, and the validity of alveolar bone loss assessed from radiographs taken at different times.

Methods: This investigation uses data obtained for a study evaluating associations between oral conditions, blood biomarkers, and coronary heart disease within two large cohorts: the Nurses' Health Study and the Health Professionals Follow-up Study. If consenting participants had dental radiographs, we requested these radiographs from their dentists.

A five-year evaluation of implants placed in extraction sockets.

The aim of this study is to examine extraction socket implant longevity and peri-implant conditions longitudinally and to compare the outcome with implants placed in intact alveolar bone sites (nonextraction sites) after a time period in function of five years or more. We hypothesize that implants placed into fresh extraction sockets have a long-term rate of success similar to that of conventionally placed implants. Eleven extraction socket implants in eight patients with a follow-up of at least five years were included in this report.

Oral hygiene practices and periodontitis in health care professionals.

Background: One in 3 adults in the United States has periodontitis, yet there are few widely applied methods for its prevention. Few studies have assessed oral hygiene practices related to periodontitis.

Methods: There were 533 participants in this study (14.

A 5-year prospective clinical and radiographic study of non-submerged dental implants.

Osseointegrated implants as anchors for various prosthetic reconstructions have become a predictable treatment alternative. It was expected that implants required submucosal placement during the healing period for successful tissue integration. However, it has been demonstrated that healing and long-term health of implants could be achieved with equal predictability in a 1-stage, non-submerged approach.