Publications by authors named "C C Coffin"
Introduction: The MiniMed™ 780G system uses an advanced hybrid closed loop algorithm to improve outcomes in people with type 1 diabetes (T1D). The MiniMed™ 780G Glycemic Control and Quality of Life (EQOL) study aimed to provide routine clinical practice data on system effectiveness and associated patient-reported outcomes (PROs) in France.
Methods: Individuals aged ≥ 7 years with T1D were enrolled.
Introduction: The molecular mechanisms underlying pressure adaptation remain largely unexplored, despite their significance for understanding biological adaptation and improving sterilization methods in the food and beverage industry. The heat shock response leads to a global stabilization of the proteome. Prior research suggested that the heat shock regulon may exhibit a transcriptional response to high-pressure stress.
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- Selective manipulation of protein interactions with chemical compounds can help understand and control plant development processes, particularly the differentiation of stomata, which are crucial for plant growth.
- The study introduces Stomidazolone, a unique compound that binds to the MUTE protein—a key regulator of stomatal differentiation—and disrupts its interaction with another protein, SCREAM.
- Through structural modeling and engineering, the researchers created modified MUTE proteins that resist Stomidazolone, demonstrating a method to potentially control stomatal development in plants.
Availability of point-of-care HBV tests in resource-limited settings.
Lancet Gastroenterol Hepatol
December 2024
Introduction And Objectives: There are limited recent data on the burden of chronic hepatitis B (CHB) in the North American general population. We aimed to identify the CHB burden from a Canadian population-based perspective.
Patients And Methods: Using a retrospective cohort design, we searched Alberta Analytics administrative databases including the Provincial Laboratory database, to describe CHB epidemiology and natural history in Alberta, Canada between fiscal years 2012-2020.