In vitro Evaluation of Cytotoxicity, Biocompatibility, and Osteogenic Effect of Two Calcium Silicate Sealers Compared with AH Plus Jet.

Objective:  The purpose of the study was to investigate the cytotoxicity, biocompatibility, and osteogenic effect of EndoSequence BCSealer HiFlow (BCH) and Bio-C Sealer (BCS) in osteosarcoma cells SAOS-2 compared with AH Plus Jet.

Materials And Methods:  For cytotoxicity analysis, the [3-(4,5-dimethyl-thiazole)-2,5-diphenyltetrazolium bromide-MTT; Sigma/Aldrich] method was used after 24, 48, and 72 hours. For cellular bioactivity, alkaline phosphatase enzyme (ALP) was evaluated after 7 and 14 days.

Temperature Changes of NaOCl after Irrigation Using Passive Ultrasonic Irrigation, Easy Clean, and XP-Endo Finisher: A Randomized Crossover Clinical Trial.

The aim of this study was to evaluate the temperature changes of sodium hypochlorite (NaOCl) after the use of different activation techniques: passive ultrasonic irrigation (PUI), XP-Endo Finisher (XP), and Easy Clean (EC).Thirty patients were selected for this randomized crossover study and each patient received root canal treatment in maxillary incisor. Each tooth was subjected to three activation techniques in a random order in the final irrigation of the treatment.

Evaluation of the Retreatability of BC Sealer, BC Sealer Hiflow, and AH Plus: A Micro-Computed Tomography Study.

Introduction: In this study, the ability to remove obturation material in canals filled with Bio C Sealer, BC Sealer Hiflow, and AH Plus was compared using micro-computed tomography.

Materials And Methods: In phase 1, 45 premolars were prepared with Reciproc Blue 25 files and divided into 3 experimental groups according to sealer and obturation techniques (n = 15): Group HI - BC Sealer Hiflow and continuous wave technique; Group AH - AH Plus and continuous wave technique; Group BC - Bio C Sealer and single cone technique. The teeth were stored for 30 days and scanned by micro-computed tomography to evaluate the volume of the obturation material.

Prenatal and Perinatal Factors Associated with Infant Acute Lymphoblastic Leukaemia: A Scoping Review.

Objective: Acute lymphoblastic leukaemia (ALL) is the most frequent childhood cancer. Infant ALL (<1 year) is rare, but it captures a lot of interest due to its poor prognosis, especially in patients harbouring rearrangements, which have been demonstrated to arise prenatally. However, epidemiological studies aimed at identifying specific risk factors in such cases are scarce, mainly due to sample-size limitations.