We aimed to understand the long-term impact of negative life events on epigenetic aging in 1783 adults from the Netherlands Twin Register, analyzing five epigenetic biomarkers (Hannum, Horvath, PhenoAge, GrimAge, DunedinPACE) and a series of negative life events, including victimization and economic hardship. In population-level analyses, associations between a higher number of negative life events (particularly financial adversities, sexual crimes, and job loss) were seen for the GrimAge biomarker. The association between the number of negative life events and financial problems and epigenetic age acceleration measured by the GrimAge biomarker persisted after adjusting for BMI, smoking, and white blood cell counts.
View Article and Find Full Text PDFSocial support is often considered an environmental factor affecting health, especially in aging populations. However, its genetic underpinnings suggest a more complex origin. This study investigates the heritability of social support through applying a threshold model on data of a large adult sample of twins ( = 8019) from the Netherlands Twin Register, collected between 2009 and 2011.
View Article and Find Full Text PDFEstablishing causal relationships in observational studies is an important step in research and policy decision making. The association between an exposure and an outcome can be confounded by multiple factors, often making it hard to draw causal conclusions. The co-twin control design (CTCD) is a powerful approach that allows for the investigation of causal effects while controlling for genetic and shared environmental confounding factors.
View Article and Find Full Text PDFWe map the available scientific literature on how and why victims of sexual violence use digital platforms in the aftermath of victimization. Twenty-four empirical studies on sexual victimization and online disclosure were identified by systematically searching Web of Science and PsycINFO, checking reference lists, and consulting authors about relevant publications. The literature on online disclosure of sexual victimization does not yield a coherent picture.
View Article and Find Full Text PDFLabeling theory suggests that criminal justice interventions amplify offending behavior. Theories of intergenerational transmission suggest why children of convicted parents have a higher risk of offending. This paper combines these two perspectives and investigates whether labeling effects might be stronger for children of convicted parents.
View Article and Find Full Text PDF