Publications by authors named "C C Beladan"

Left ventricular (LV) diastolic dysfunction, atrial fibrillation (AF), and heart failure with preserved ejection fraction (HFpEF) share common risk factors and are closely related to one another and to adverse cardiovascular events. Exertional dyspnoea in patients with AF should trigger a comprehensive LV diastolic function evaluation since AF frequently precedes incident HFpEF. An echocardiographic assessment of LV diastolic function in patients with AF is challenging, mainly because of variability in cycle length, the absence of atrial contraction, and the frequent occurrence of left atrial enlargement regardless of LV filling pressures (LVFPs).

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Background: Echocardiography is widely used to evaluate left ventricular (LV) diastolic function in patients suspected of heart failure. For patients in sinus rhythm, a combination of several echocardiographic parameters can differentiate between normal and elevated LV filling pressure with good accuracy. However, there is no established echocardiographic approach for the evaluation of LV filling pressure in patients with atrial fibrillation.

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Article Synopsis
  • The study investigates the role of right ventricular (RV) to pulmonary artery (PA) coupling in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI).
  • Significant improvements in RV-PA coupling were observed shortly after TAVI, primarily due to a decrease in pulmonary artery systolic pressure (PASP).
  • Impaired RV-PA coupling was linked to lower survival rates in patients, with factors like left atrial strain and RV diameter being significant predictors of RV-PA coupling impairment.
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