Publications by authors named "C C Barr"

Psychologically informed practice is a structural framework originating in physiotherapy, that aids clinicians to identify, consider, and address the psychological factors related to chronic conditions and their management. Hearing loss is a chronic condition associated with a variety of psychosocial impacts, and psychological factors are known to heavily influence the engagement, adherence, and success of hearing rehabilitation. This framework could provide a structured method to manage these factors by using evidence-based psychological theory and applications.

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Vancomycin-resistant Staphylococcus aureus (VRSA) is a rare but serious public health concern. We describe a VRSA case in North Carolina, USA. The isolate from the case belonged to the USA600 lineage and clonal complex 45.

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The mitochondrial DNA (mtDNA) can trigger immune responses and directly entrap pathogens, but it is not known to encode for active immune factors. The immune system is traditionally thought to be exclusively nuclear-encoded. Here, we report the identification of a mitochondrial-encoded host defense peptide (HDP) that presumably derives from the primordial proto-mitochondrial bacteria.

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Article Synopsis
  • * It involves 140 participants aged 60 and older with untreated OSA, randomizing them into two groups: one receiving CPAP along with usual care for fall prevention, and the other receiving only the usual care.
  • * The study will assess various outcomes including fall risk scores, gait, and overall health, with results intended for publication and future guidelines on fall prevention in older adults.
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  • The study investigates the safety and effectiveness of various DMARDs, including methotrexate (MTX), tofacitinib, tumor necrosis factor inhibitors (TNFi), and non-TNFi biologic DMARDs, in patients with rheumatoid arthritis (RA) using data from the CorEvitas RA Japan registry.
  • Safety outcomes measured include major cardiovascular events, serious infections, herpes zoster, and malignancies, while effectiveness was measured using the Clinical Disease Activity Index (CDAI).
  • Findings show that MTX and TNFi had lower rates of adverse cardiovascular events compared to tofacitinib and non-TNFi, but tofacitinib demonstrated superior effectiveness in improving CDAI scores at 6 months
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