New Germline TP53 Variant Detected After Radiotherapy-Induced Angiosarcoma of the Chest Wall in a Previously Treated Breast Cancer Patient: A Case Report and Review of Li-Fraumeni Syndrome and Radiotherapy-Induced Sarcoma.

Li-Fraumeni syndrome (LFS) is one of the most common hereditary cancer predisposition syndromes in Brazil. The high frequency of the syndrome is due to a founding variant (R337H) in the country. LFS is characterized by a wide variety of malignant phenotypes.

Patterns of recurrence following radiation and ADT for pathologic lymph node positive prostate cancer: A multi-institutional study.

Background And Objective: We evaluate prognostic factors and patterns of recurrence in patients who received RT ± androgen deprivation therapy (ADT) for pathologic node-positive (pN1) prostate cancer (PCa) in a multi-institutional cohort.

Methods: Data from patients with pN1 PCa and received RT with short term (ST, ≤6 mo) or long term (LT, >6 mo) ADT were obtained from 4 academic institutions. Biochemical progression free survival (bPFS) and distant metastasis free survival (DMFS) were evaluated.

The relevance of degenerate states in chiral polaritonics.

In this work, we theoretically explore whether a parity-violating/chiral light-matter interaction is required to capture all relevant aspects of chiral polaritonics or if a parity-conserving/achiral theory is sufficient (e.g., long-wavelength/dipole approximation).

New evidence confirms the presence of the diamond stingray Hypanus dipterurus (Jordan & Gilbert 1880) in Chile and extends its southern range.

The diamond stingray (Hypanus dipterurus) is a species of cartilaginous fish that, according to the IUCN, is globally in a vulnerable state of conservation and its populations show a decline. New records of this ray species in southern Peru and northern Chile have expanded their known range. The species is distributed in the Eastern Central Pacific, from southern California to San Andres, on the central coast of Peru, but is poorly known in Chile.

Characterization of ZAT12 protein from Prunus persica: role in fruit chilling injury tolerance and identification of gene targets.

PpZAT12, a transcription factor differentially expressed in peach varieties with distinct susceptibility tochilling injury (CI), is a potential candidate gene for CI tolerance by regulating several identified gene targets. ZAT (zinc finger of Arabidopsis thaliana) proteins play roles in multiple abiotic stress tolerance in Arabidopsis and other species; however, there are few reports on these transcription factors (TFs) in fruit crops. This study aimed to evaluate PpZAT12, a C2H2 TF up-regulated in peach fruit by a heat treatment applied before postharvest cold storage for reducing chilling injury (CI) symptoms.