Publications by authors named "C Brun-Buisson"
Article Synopsis
- - The study analyzed the effects of the COVID-19 pandemic and its aftermath on hospital admissions for lower respiratory tract infections (LRTI), focusing specifically on patients with chronic respiratory disease (CRD) over a ten-year period.
- - Data showed a significant drop in LRTI hospitalizations during the early pandemic and post-lockdown periods compared to pre-pandemic averages, with a 43.64% decrease during the early pandemic and 32.97% during the gradual lifting of restrictions.
- - After restrictions were lifted, there was a notable rebound in LRTI admissions that returned to seasonal patterns, indicating that COVID-19 mitigation strategies affected infection rates, particularly in patients with CRD.
We investigated links between antimicrobial resistance in community-onset bacteremia and 1-year bacteremia recurrence by using the clinical data warehouse of Europe's largest university hospital group in France. We included adult patients hospitalized with an incident community-onset Staphylococcus aureus, Escherichia coli, or Klebsiella spp. bacteremia during 2017-2019.
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- The study explores the effectiveness of hydrocortisone and fludrocortisone treatments in patients with septic shock caused by community-acquired pneumonia (CAP) compared to non-CAP cases.
- It includes data from the phase 3 APROCCHSS trial, which initially tested these treatments across multiple centers in France, focusing specifically on how they impact mortality outcomes.
- Results indicate that patients with CAP may respond differently to these treatments, and various mortality rates and recovery metrics were analyzed to determine the overall benefit of the steroid regimen.
Article Synopsis
- Nosocomial pneumonia, which is a lung infection that people can get while in the hospital, leads to higher rates of sickness and death and costs a lot to treat, especially in ICUs (Intensive Care Units).
- Most cases of this type of pneumonia happen in patients on ventilators, which helps them breathe.
- The PneumoINSPIRE study is looking at how this pneumonia is diagnosed and treated in ICUs from over 20 countries to gather important information about it and improve future care.
Background: Individuals who survive sepsis are at high risk of chronic sequelae, resulting in significant health-economic costs. Several studies have focused on aspects of healthcare pathways of sepsis survivors but comprehensive, longitudinal overview of their pathways of care are scarce. The aim of this retrospective, longitudinal cohort study is to identify sepsis survivor profiles based on their healthcare pathways and describe their healthcare consumption and costs over the 3 years following their index hospitalization.
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