Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding.

Introduction: Skeletal muscle satellite cells (MuSCs or stem cells) play a crucial role in muscle development, maintenance, and regeneration, supporting both hypertrophy and regenerative myogenesis. Syndecans (SDCs) act as communication bridges within the muscle microenvironment, regulating interactions with extracellular matrix components and contributing significantly to tissue repair and inflammation. Specifically, syndecan-4 (SDC4) is involved in muscle regeneration at multiple stages.

Stereotactic Cardiac Radiotherapy for Refractory Ventricular Tachycardia in Structural Heart Disease Patients: A Systematic Review.

Background: Among patients with structural heart disease with ventricular tachycardia (VT) refractory to medical therapy and catheter ablation, cardiac stereotactic body radiotherapy (SBRT) is a paradigm-changing treatment option.

Aims: To assess the efficacy of cardiac SBRT in refractory VT by comparing the rates of VT episodes, anti-tachycardia pacing (ATP) therapies, and implantable cardioverter-defibrillator (ICD) shocks post-SBRT with pre-SBRT.

Methods: We performed a comprehensive literature search and included all clinical studies reporting outcomes on cardiac SBRT for VT.

Tunneling and conformational preferences in racemic- and meso-2,4-pentanediol: A rotational spectroscopic and theoretical investigation.

The rotational spectra of a mixture of 2,4-pentanediol (PDL) isomers, comprising both the meso isomers [(2R, 4S) and (2S, 4R)] and the racemic isomers [(2R, 4R) and (2S, 4S)], were recorded using a chirped-pulse Fourier transform microwave spectrometer coupled to a supersonic jet expansion. The conformational landscapes of meso- and racemic-PDL were examined using the Conformer-Rotamer Ensemble Sampling Tool and high-level quantum chemical calculations, generating 26 and 25 conformers, respectively. Five sets of rotational transitions were observed and assigned, with two attributed to meso-PDL and the remaining three attributed to racemic-PDL.

Low-cost and label-free blue light cystoscopy through digital staining of white light cystoscopy videos.

Background: Bladder cancer is the 10 most common malignancy and carries the highest treatment cost among all cancers. The elevated cost stems from its high recurrence rate, which necessitates frequent surveillance. White light cystoscopy (WLC), the standard of care surveillance tool to examine the bladder for lesions, has limited sensitivity for early-stage bladder cancer.

Implementation of tele-geriatricmental healthcare for rural veterans: factors influencing care models.

Introduction: Aging rural veterans have limited access to geriatric mental health services. The establishment of Veterans Health Administration (VHA) regional telehealth hubs, or Clinical Resource Hubs (CRHs), has the potential to improve access to specialist care via telehealth delivered across healthcare systems within each VHA region. We used the Consolidated Framework for Implementation Research (CFIR 1.