Publications by authors named "C Briquet"

Article Synopsis
  • Linezolid is a special antibiotic used when other antibiotics don't work, but it can cause side effects like low platelet counts (thrombocytopenia).
  • Researchers studied patients taking Linezolid to find out how often these side effects happen and what might increase the risk, especially with longer treatments and higher drug levels in the blood.
  • They found that patients on Linezolid for more than 10 days or with high blood levels were more likely to have problems, and they suggested ways to monitor and adjust treatment to keep patients safe.
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Introduction: Inappropriate antibiotic use is a major cause of antibiotic resistance. Therefore, optimizing antibiotic usage is essential. In Belgium, optimization of antimicrobials for the fight against multidrug resistant organisms (MDROs) is followed up by national surveillance by public health authorities.

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Objectives: Clostridioides difficile infection (CDI) causes the greatest number of healthcare-associated infectious diarrhoea. CDIs are transmitted by direct and indirect patient-to-patient contact and risk increases with the use of antibiotics. Since early 2020, the COVID-19 pandemic has affected healthcare systems in many ways including substantial changes in hygiene behaviour.

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Objectives: This study aimed to identify barriers to the proper use of antibiotics by healthcare professionals and to help the hospital Antimicrobial Stewardship develop suitable actions for the staff.

Methods: In a Belgian teaching hospital, a survey was conducted among physicians, pharmacists, and nurses involved in antibiotherapy. Questions from the 2019 European Center for Disease Prevention and Control (ECDC) survey were analyzed based on components of the COM-B model (capabilities, opportunities, and motivations).

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