Digital breast tomosynthesis versus mammography and breast ultrasound: a multireader performance study.

Objectives: To compare the diagnostic performance of single-view breast tomosynthesis (BT) with that of dual-view mammography (MX); to assess the benefit of adding the craniocaudal (CC) mammographic view to BT, and of adding BT to MX plus breast ultrasound, considered to be the reference work-up.

Methods: One hundred and fifty-five consenting patients with unresolved mammographic and/or ultrasound findings or breast symptoms underwent conventional work-up plus mediolateral oblique-view BT of the affected breast. The final study set in 130 patients resulted in 55 malignant and 76 benign and normal cases.

Ultrasound elastography as an objective diagnostic measurement tool for lymphoedema of the treated breast in breast cancer patients following breast conserving surgery and radiotherapy.

BACKGROUND.: Lymphoedema of the operated and irradiated breast is a common complication following early breast cancer treatment. There is no consensus on objective diagnostic criteria and standard measurement tools.

Initial axillary staging of breast cancer using ultrasound-guided fine needle aspiration: a liquid-based cytology study.

Objective: To evaluate the preoperative detection of axillary metastasis combining ultrasound (US)-guided fine needle aspiration cytology (FNAC) and liquid-based cytology (Surepath(®)) to reduce sentinel node procedures.

Methods: In total, 148 patients with clinically negative lymph nodes and no preoperative therapy were included. All patients underwent preoperative ultrasound of the axilla with FNAC if suspicious lymph nodes were found.

Development of a multi-spectral, multi-geometry computational model for X-ray breast imaging.

The introduction of novel applications in X-ray breast imaging warrants new research for image acquisition optimisation. A simulation model was developed to investigate the influence of different imaging techniques and acquisition parameters. It was modelled in Monte Carlo N-Particle Extended and contains an X-ray tube with photon production, a breast model and antiscatter grid model.