The Experiences of Native Irish speaking Older Adults Navigating Healthcare Services.

Aim: This research aims to understand the experiences of native Irish speaking older adults navigating healthcare services in Ireland.

Methods: Semi-structured interviews in the Irish language were conducted with seven participants. Interviews were audio recorded and transcribed.

Manipulation of the inflammatory reflex as a therapeutic strategy.

The cholinergic anti-inflammatory pathway is the efferent arm of the inflammatory reflex, a neural circuit through which the CNS can modulate peripheral immune responses. Signals communicated via the vagus and splenic nerves use acetylcholine, produced by Choline acetyltransferase (ChAT)+ T cells, to downregulate the inflammatory actions of macrophages expressing α7 nicotinic receptors. Pre-clinical studies using transgenic animals, cholinergic agonists, vagotomy, and vagus nerve stimulation have demonstrated this pathway's role and therapeutic potential in numerous inflammatory diseases.

Sexual assault and fatal violence against women during the Irish War of Independence, 1919-1921: Kate Maher's murder in context.

At the height of the Irish War of Independence, 1919-1921, 45-year-old Kate Maher was brutally raped. She subsequently died of terrible wounds, almost certainly inflicted by drunken British soldiers. This article discusses her inadequately investigated case in the wider context of fatal violence against women and girls during years of major political instability.

Expression of in the Stem Cell Domain Is Required for Its Function in the Control of Floral Meristem Activity in .

In the model plant , the zinc-finger transcription factor KNUCKLES (KNU) plays an important role in the termination of floral meristem activity, a process that is crucial for preventing the overgrowth of flowers. The gene is activated in floral meristems by the floral organ identity factor AGAMOUS (AG), and it has been shown that both AG and KNU act in floral meristem control by directly repressing the stem cell regulator (), which leads to a loss of stem cell activity. When we re-examined the expression pattern of in floral meristems, we found that is expressed throughout the center of floral meristems, which includes, but is considerably broader than the expression domain.