Localization of a conformational energy-coupling determinant near the C terminus of the beta subunit of the F1F0-ATPase.

Escherichia coli mutants in the beta subunit of the F1F0-ATPase can be complemented with the beta subunit from the obligate aerobe Bacillus megaterium. It has been shown that cells carrying such hybrid ATPases have an unusual energy-coupling phenotype. Although they are able to grow on minimal succinate medium, and therefore carry a functional ATP synthase, they are defective in the ability to grow anaerobically, indicating some defect in ATP-driven proton pumping (Scarpetta, M.

Effects of BM 13.177, a new antiplatelet drug in patients with atherosclerotic disease.

Seven males with atherosclerotic disease received daily 1.6 g of the thromboxane antagonist BM 13.177 in two separate oral dosages over a period of four days.

Guar and its effects on metabolic control in type II diabetic subjects.

The effect of guar mini-tablets (5 g t.i.d.

Guar gum and bile: effects on postprandial gallbladder contraction and on serum bile acids in man.

In a randomized cross-over study, 10 healthy volunteers received a fiber-depleted liquid mixed meal alone and, exactly 7 days apart, a combination with 15 g guar gum. Addition of the dietary fiber inhibited emptying of the gall bladder after 30 min to 7 (5-10) ml instead of 4 (3-6) ml (p less than 0.05) and delayed its refilling.