Publications by authors named "C Bourantas"
Background And Aims: Coronary angiography-derived wall shear stress (WSS) may enable identification of vulnerable plaques and patients. A new recently introduced software allows seamless three-dimensional quantitative coronary angiography (3D-QCA) reconstruction and WSS computation within a single user-friendly platform carrying promise for clinical applications. This study examines for the first time the efficacy of this software in detecting vulnerable lesions in patients with intermediate non-flow limiting stenoses.
View Article and Find Full Text PDFTraditionally, coronary angiography was restricted to visual estimation of contrast-filled lumen in coronary obstructive diseases. Over the previous decades, considerable development has been made in quantitatively analyzing coronary angiography, significantly improving its accuracy and reproducibility. Notably, the integration of artificial intelligence (AI) and machine learning into quantitative coronary angiography (QCA) holds promise for further enhancing diagnostic accuracy and predictive capabilities.
View Article and Find Full Text PDFLinking Physiology and Biology in Plaque Erosion: A Gordian Knot.
JACC Basic Transl Sci
November 2024
Article Synopsis
- Coronary computed tomography angiography (CCTA) was evaluated as an alternative to intravascular imaging techniques for assessing plaque pathology in patients with chronic coronary syndrome.
- The study involved 70 patients and compared CCTA with near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) to analyze atheroma burden and composition, focusing on the accuracy of detecting lipid-rich plaques.
- Results showed that CCTA had limitations in accurately measuring plaque dimensions and composition, leading to potential issues in planning for coronary interventions.
CTCA Prior to Invasive Coronary Angiography in Patients With Previous Bypass Surgery: Patient-Related Outcomes, Imaging Resource Utilization, and Cardiac Events at 3 Years From the BYPASS-CTCA Trial.
Circ Cardiovasc Interv
December 2024
Article Synopsis
- The BYPASS-CTCA trial found that using computed tomography cardiac angiography (CTCA) prior to invasive coronary angiography (ICA) in patients with previous bypass surgery reduces procedure time and the risk of kidney injury, improving patient satisfaction.
- In this study, 688 patients were divided into two groups: one receiving CTCA before ICA and the other receiving ICA alone, with follow-up averaging 3 years.
- Results showed that although benefits like being angina-free and improved quality of life were seen at 3 months, long-term outcomes showed CTCA/ICA patients had lower imaging resource use and fewer major adverse cardiac events compared to those who only had ICA.