We combine measurements of galaxy velocities from galaxy surveys with measurements of the Weyl potential from the Dark Energy Survey to test the consistency of general relativity at cosmological scales. Taking the ratio of two model-independent observables-the growth rate of structure and the Weyl potential-we obtain new measurements of the E_{G} statistic with precision of 6.0-11.
View Article and Find Full Text PDFBackground: There are limited real-world data in Switzerland examining the impact of erenumab, a fully human IgG2 monoclonal antibody targeting the calcitonin gene-related peptide (CGRP) receptor, on migraine-related quality of life.
Objective: This 18-month interim analysis of 172 patients with episodic or chronic migraine from the SQUARE study provides first prospective insights on the impact of mandatory erenumab treatment interruption, following Swiss-reimbursement requirements, in a real-world clinical setting in Switzerland.
Findings: Recruited patients receiving 70 or 140 mg erenumab underwent treatment interruption on average 11.
Background: Cortical excitation/inhibition dynamics have been suggested as a key mechanism occurring after stroke. Their supportive or maladaptive role in the course of recovery is still not completely understood. Here, we used transcranial magnetic stimulation (TMS)-electroencephalography coupling to study cortical reactivity and intracortical GABAergic inhibition, as well as their relationship to residual motor function and recovery longitudinally in patients with stroke.
View Article and Find Full Text PDFBackground: Ischaemic stroke may occur despite antiplatelet therapy (APT). We aimed to investigate frequency, potential causes and outcomes in patients with ischaemic stroke despite APT.
Methods: In this cohort study, we enrolled patients with imaging-confirmed ischaemic stroke from the Swiss Stroke Registry (01/2014-07/2022).