Publications by authors named "C Bonnafoux"
Article Synopsis
- The study focused on improving the detection of anti-dsDNA antibodies, crucial for diagnosing systemic lupus erythematosus, by comparing two testing techniques: ELISA and CLIFT.
- Researchers analyzed 1,729 tests over 18 months, using CLIFT for cases that didn't match ELISA results or based on clinical data, leading to 96 CLIFT tests conducted.
- Findings showed that using both techniques increased sensitivity, identifying additional lupus cases and revealing potential false positives from ELISA, validating the dual approach for cost-effective lab use.
[Dense cytoplasmic fluorescence on Hep-2 cells: do not overlook anti-PL].
Pathol Biol (Paris)
February 2008
Objective: Any dense cytoplasmic fluorescence on Hep-2000 cells seen in the immunology laboratory of the Clermont-Ferrand teaching hospital was closely studied to determine the presence or not of anti-PL antibodies.
Patients And Methods: From January 2006 to January 2007, twelve patients presented a dense cytoplasmic fluorescence on Hep-2000 cells. So we activated a Hep-2 cells'slide, a triple substrate's slide and a dot in order to exclude antiribosomes and anti-JO1 antibodies.