Publications by authors named "C Boersma"
Anharmonic computations reveal an intense, narrow (20 cm, 0.043 μm) absorption feature at approximately 2160 cm (4.63 μm) in the vibrational spectra of 14 prototypical singly isocyano-substituted polycyclic aromatic hydrocarbons (NC-PAHs) attributed to the NC stretching mode.
View Article and Find Full Text PDFAim: The recent EMPA-KIDNEY trial showed evidence for preventing disease progression in adult patients with chronic kidney disease (CKD) treated with empagliflozin. It is however yet unknown if use of empagliflozin is cost effective in the Netherlands. We aimed to evaluate the cost effectiveness of empagliflozin in adult patients with CKD in the Netherlands.
View Article and Find Full Text PDFStrong anharmonic coupling between vibrational states in polycyclic aromatic hydrocarbons (PAH) produces highly mixed vibrational transitions that challenge the current understanding of the nature of the astronomical mid-infrared PAH emission bands. Traditionally, PAH emission bands have been characterized as either aromatic or aliphatic, and this assignment is used to determine the fraction of aliphatic carbon in astronomical sources. In reality, each of the transitions previously utilized for such an attribution is highly mixed with contributions from both aliphatic and aromatic CH motions as well as non-CH motions such as CC stretches.
View Article and Find Full Text PDFArticle Synopsis
- - Comparative effectiveness research (CER) helps in assessing the safety and effectiveness of new drugs versus existing treatments, aiding better healthcare decisions and aligning new therapies with patient needs.
- - A systematic literature review was conducted to gather existing regulatory and health technology assessment guidelines for CER, ultimately identifying the absence of clear analytical approaches tailored to specific situations.
- - To address this gap, a methods flowchart was created to guide analysts in choosing appropriate CER methodologies, fostering consistent research quality and supporting evidence-based healthcare decisions.
Background: Although both hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) are covered by national healthcare insurance, 98% of kidney failure disease patients are treated with hemodialysis. This study compared the health-related quality of life (HRQoL) and utility scores of patients receiving hemodialysis and CAPD in Indonesia and determined factors associated with HRQoL and utility scores.
Methods: A cross-sectional study was performed using the Kidney Disease Quality of Life-36 and EQ-5D-5L instruments at six hospitals.