Publications by authors named "C Bodian"
Background & Aims: Patients with colitis have an increased risk of colorectal cancer, compared with persons without colitis. Many studies have shown chromoendoscopy (CE) to be superior to standard methods of detecting dysplasia in patients with colitis at index examination. We performed a prospective, longitudinal study to compare standard colonoscopy vs CE in detecting dysplasia in patients with inflammatory bowel diseases in a surveillance program.
View Article and Find Full Text PDFBackground And Study Aims: Surveillance intervals after colonoscopic resection of serrated polyps are partially predicated on the histology of the polyp(s) removed during the index exam. Histologic discrimination between sessile serrated adenomas/polyps (SSA/P) and hyperplastic polyps is challenging. We devised and tested a simple tool--an envelope--that gastroenterologists can integrate into routine colonoscopy practice to address this problem.
View Article and Find Full Text PDFArticle Synopsis
- The BRCA1 gene is a tumor suppressor vital for DNA damage repair and its protein is mainly found in cell nuclei; deficiencies can lead to worse breast cancer outcomes.
- A study analyzed BRCA1 protein distribution in 22 breast cancer samples, comparing tissue types and assessing mutations linked to BRCA1 and BRCA2.
- Results showed reduced BRCA1 staining in tumor tissue versus normal tissue, especially in higher-grade tumors, and mutations altered how BRCA1 localized within cells, highlighting its importance in breast cancer development.
Economic and safety implications of introducing fast tracking in congenital heart surgery.
Circ Cardiovasc Qual Outcomes
March 2013
Background: The feasibility of fast-tracking children undergoing congenital heart disease surgery has not been assessed adequately. Current knowledge is based on limited single-center experiences without contemporaneous control groups.
Methods And Results: We compared administrative data for atrial septal defect (ASD) and ventricular septal defect (VSD) surgeries in children 2 months to 19 years of age at the Mount Sinai Medical Center (MSMC) with data from comparable patients at 40 centers contributing to the Pediatric Health Information System.