Publications by authors named "C Blein"

Background And Purpose: Few data are available on the course of myasthenia gravis (MG) regarding disease severity and stability over time in real-world settings. This study used the French National Health Insurance Database (SNDS) to assess markers of disease severity in patients with MG longitudinally.

Methods: All patients with MG-related claims in the SNDS between 2013 and 2020 were identified.

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Purpose: The value of intravascular ultrasound (IVUS) guidance during peripheral vascular revascularization procedures is incompletely understood. Moreover, data on long-term clinical outcomes and costs are limited. The objective of this study was to compare outcomes and costs between IVUS and contrast angiography alone in patients undergoing peripheral revascularization procedures in Japan.

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Background & Aims: Wilson disease (WD) is a rare hereditary, debilitating disease that is fatal if untreated. Given its low prevalence, collecting longitudinal information on large cohorts of patients is challenging. Analysis of health insurance databases offers an approach to meet this challenge.

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Article Synopsis
  • - The study assessed the public health impact of COVID-19 on French patients with risk factors, using a Markov model to estimate various outcomes like hospitalizations, deaths, and costs over two years.
  • - Results indicated a significant burden with 256 hospitalizations per 1,000 patients in the first month and 382 over two years, along with 37 deaths and 407 cases of long COVID.
  • - The findings highlight an urgent need for effective strategies to reduce COVID-19 burden, especially among older and unvaccinated patients, with notable cost implications for healthcare.
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Background: Territorial differences in the access to innovative anticancer drugs have been reported from many countries. The objectives of this study were to evaluate access to innovative treatments for metastatic lung cancer in France, and to assess whether socioeconomic indicators were predictors of access at the level of the municipality of residence.

Methods: All incident cases of metastatic lung cancer hospitalised for a chemotherapy in public hospitals in 2011 were identified from the French National Hospital discharge database.

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