Publications by authors named "C Biryabarema"
Self-collection based HPV testing for cervical cancer screening among women living with HIV in Uganda: a descriptive analysis of knowledge, intentions to screen and factors associated with HPV positivity.
BMC Womens Health
January 2017
Background: Women living with HIV (WHIV) are disproportionately impacted by cervical dysplasia and cancer. The burden is greatest in low-income countries where limited or no access to screening exists. The goal of this study was to describe knowledge and intentions of WHIV towards HPV self-collection for cervical cancer screening, and to report on factors related to HPV positivity among women who participated in testing.
View Article and Find Full Text PDFIntroduction: Community engagement and education can improve acceptability and participation in clinical trials conducted in Kisenyi, Uganda. In preparation for a randomized controlled trial exploring different methods for cervical cancer screening, we explored optimal engagement strategies from the perspective of community members and health professionals.
Methods: We conducted key informant interviews followed by serial community forums with purposeful sampling and compared the perspectives of women in Kisenyi (N = 26) to health-care workers (HCW) at the local and tertiary care center levels (N = 61) in a participatory, iterative process.
Objectives: To compare two cervical cancer screening methods: community-based self-collection of high-risk human papillomavirus (HR-HPV) testing and visual inspection with acetic acid (VIA).
Methods: Pilot randomised controlled trial of 500 women aged 30-65 in the community of Kisenyi, Uganda. Women randomised to self-collection-based HR-HPV testing provided a cervico-vaginal swab for HR-HPV, and results were provided by phone after laboratory testing.
Objective: To define embarrassment and develop an understanding of the role of embarrassment in relation to cervical cancer screening and self-collected human papillomavirus (HPV) DNA testing in Uganda.
Design: Cross-sectional, qualitative study using semistructured one-to-one interviews and focus groups.
Participants: 6 key-informant health workers and 16 local women, purposively sampled.
A risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: the miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) multi-country prospective cohort study.
PLoS Med
January 2014
Article Synopsis
- Pre-eclampsia and eclampsia are serious complications of pregnancy that significantly contribute to maternal mortality, especially in low- and middle-income countries (LMICs), prompting the development of the miniPIERS risk prediction model for better risk assessment.
- Data from over 2,000 women with hypertensive pregnancy disorders were analyzed using a logistic regression model, resulting in a prediction tool that considers various clinical factors such as gestational age and blood pressure to identify women at high risk of severe complications.
- The miniPIERS model demonstrated good predictive accuracy, with an AUC ROC of 0.768 for internal validation and 0.713 for external validation, indicating its potential effectiveness in clinical settings despite some limitations related to its broad inclusion