Publications by authors named "C Bilu"

Circadian disruption causes glucose intolerance, cardiac fibrosis, and adipocyte dysfunction in sand rats (). Exercise intervention can improve glucose metabolism, insulin sensitivity, adipose tissue function and protect against inflammation. We investigated the influence of exercise on male exposed to a short photoperiod (5 h light:19 h dark) and high-energy diet.

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Circadian disruption increases the development of cardiovascular disease and diabetes. We found that circadian disruption causes glucose intolerance, cardiac fibrosis and adipocyte tissue dysfunction in male sand rats, . Whether these effects occur in female is unknown.

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Article Synopsis
  • Circadian syndrome (CircS) is a more significant predictor of cognitive impairment compared to metabolic syndrome (MetS) in Chinese adults aged 40 and older.
  • CircS consists of MetS components plus short sleep and depression, showing a negative impact on global cognition scores, while MetS alone seems to correlate with better cognitive function.
  • Individuals with CircS are significantly more likely to report poor memory, whereas MetS appears to have a protective effect against memory issues.
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Type 2 diabetes mellitus (T2DM) and its ocular complications, such as cataract and diabetic retinopathy (DR) have been linked to circadian rhythm-disturbances. Using a unique diurnal animal model, the sand rat (Psammomys obesus) we examined the effect of circadian disruption by short photoperiod acclimation on the development of T2DM and related ocular pathologies. We experimented with 48 male sand rats.

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The study aimed to compare the predictive value of the Circadian Syndrome (CircS) and Metabolic Syndrome (MetS) for cardiovascular disease (CVD). We used data of 12,156 adults aged ≥20 years who attended National Health and Nutrition Examination Survey (NHANES) 2005-2016. Mortality was obtained from the registry updated to 2019.

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