Publications by authors named "C Beyls"
Article Synopsis
- Non-steroidal anti-inflammatory drugs (NSAIDs) are often used for managing acute postoperative pain after surgery, but their use in cardiac procedures raises concerns about risks like increased bleeding and kidney injury.
- The KETOPAIN trial aims to evaluate the effectiveness and safety of ketoprofen in treating postoperative pain in cardiac surgery patients, involving 238 participants randomized to receive either ketoprofen or a placebo after the procedure.
- The study will assess various outcomes, including pain intensity at 24 hours post-surgery, opioid consumption, complications, and quality of life up to three months afterward.
Article Synopsis
- SCN5A gene variants are linked to various cardiac electrical disorders, but they can also result in complex phenotypes like overlap syndromes, which haven't been thoroughly studied.
- The study analyzed DNA from over 13,500 patients with a focus on those carrying pathogenic SCN5A variants, finding that most were tied to well-defined conditions like Brugada syndrome and long QT syndrome.
- About 19% of the variants were associated with complex phenotypes, and only a small number (8 out of 9,960 patients) showed a potential link to dilated cardiomyopathies (DCM), suggesting it's a rare association.
Introduction: Norepinephrine (NE) is the first-line recommended vasopressor for restoring mean arterial pressure (MAP) in vasoplegic syndrome (vs) following cardiac surgery with cardiopulmonary bypass. However, solely focusing on target MAP values can lead to acute hypotension episodes during NE weaning. The Hypotension Prediction Index (HPI) is a machine learning algorithm embedded in the Acumen IQ device, capable of detecting hypotensive episodes before their clinical manifestation.
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