Publications by authors named "C Bettag"
Background/aim: Biomarkers for patients suffering from glioblastoma (GBM) are scarce. Extracellular vesicles (EV) are a promising candidate for a potential biomarker. Therefore, EV concentration could be a potential biomarker of tumor burden, volume, and prognosis.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the impact of endoscope-assisted fluorescent-guided surgery on the outcomes of glioblastoma patients, focusing on the extent of tumor resection and survival rates.
- It compares data from 114 patients, finding that endoscopic assistance led to a higher rate of gross total resection (100% vs. 75.9%) and improved progression-free survival (PFS) and overall survival (OS).
- The researchers conclude that while endoscope-assisted surgery shows promising results for enhancing tumor removal and survival, further prospective studies are needed to confirm their findings due to limitations in the current study design.
Purpose: Spinal augmentation procedures (SAP) are standard procedures for vertebral compression fractures. Often, SAPs are carried out in a minimally invasive, percutaneous way. Certain anatomic conditions such as small pedicles or kyphotic deformities resulting from a significant collapse of the vertebral body might render the operation more difficult and increase the risk of complications.
View Article and Find Full Text PDFObjective: Fluorescence-guided resection of cerebral metastases has been proposed as an approach to visualize residual tumor tissue and maximize the extent of resection. Critics have argued that tumor cells at the resection margins might be overlooked under microscopic visualization because of technical limitations. Therefore, an endoscope, which is capable of inducing fluorescence, has been applied with the aim of improving exposure of fluorescent tumor tissue.
View Article and Find Full Text PDFImpact of COVID-19 on the Neurosurgical Resident Training Program: An Early Experience.
J Neurol Surg A Cent Eur Neurosurg
July 2022
Background: The present study evaluates the impact of COVID-19 pandemic restrictions during the first lockdown period in spring 2020 on the neurosurgical resident training program, and provides constructive approaches to deal with such situations.
Methods: A concurrent embedded mixed methods design was used. Qualitative data were collected through in-depth interviews from all neurosurgical residents at three university hospitals in Germany.