Publications by authors named "C Baudoin"

Article Synopsis
  • - DFNA68 is a rare form of hearing impairment caused by specific mutations in the HOMER2 gene, with only 5 known variants reported in families affected by this condition.
  • - A new gene variation (c.1064 A > G) was discovered in a Sicilian family, leading to the production of a longer HOMER2 protein, which was shown to impact hearing negatively.
  • - The research utilized zebrafish models to confirm the harmful effects of this new genetic alteration on hearing, expanding the understanding of DFNA68's genetic basis.
View Article and Find Full Text PDF

Traumatic events such as hospitalization of family members in the intensive care setting can influence communication interactions between health-care workers and family members not just because of the acute situation but because it brings feelings resulting from past traumatic events to the surface. Providing trauma-informed care to all patients and families in the critical care setting improves communication and results in encounters that are less likely to result in an escalation of negative emotions and outbursts and provides an environment that is conducive to interprofessional communication between families, patients, and health-care workers.

View Article and Find Full Text PDF

Health care is shifting toward become proactive according to the concept of P5 medicine-a predictive, personalized, preventive, participatory and precision discipline. This patient-centered care heavily leverages the latest technologies of artificial intelligence (AI) and robotics that support diagnosis, decision making and treatment. In this paper, we present the role of AI and robotic systems in this evolution, including example use cases.

View Article and Find Full Text PDF

Information systems used by platform trials should handle changes that are not predefined. Unfortunately, the technical architecture of most existing clinical data management systems (CDMS) do not support changes to be incorporated into an ongoing trial. Adaptive clinical trials need advanced architectural solutions setup to enable biomarker stratification and enrichment strategy necessary for the adaptive clinical trial operation.

View Article and Find Full Text PDF

The COVID-19 pandemic and nursing shortage has impacted new graduate nurse (NGN) careers. Many NGNs gain initial employment with intensive care areas, encountering unprecedented stress due to high patient acuities, technology, and deaths. Having not yet transitioned into nursing practice, the NGN can experience a reality shock.

View Article and Find Full Text PDF