Laparoscopic nerve-sparing surgery of deep infiltrating endometriosis: description of the technique and patients' outcome.

Introduction: The radical surgery of the deep infiltrating endometriosis of the rectovaginal septum and the uterosacral ligaments with or without bowel resection can cause a serious damage of the pelvic autonomic nerves with urinary retention and the need of self-catheterization.

Patients And Methods: We introduce a case series report of 16 patients with laparoscopic nerve-sparing surgery of deep infiltrating endometriosis. We describe the technique step by step and compare the patients' outcome with patients who had undergone a non-nerve-sparing surgical technique.

Laparoscopic management of ectopic pregnancy during a 9-year period.

The present study analyzed the epidemiology and outcome of ectopic pregnancy during a 9-year period on a total of 473 women. Our follow-up shows that laparoscopic salpingostomy, performed in 84.9% of the patients, is a safe and effective treatment for ectopic pregnancy.

94 months follow-up after laparoscopic assisted vaginal resection of septum rectovaginale and rectosigmoid in women with deep infiltrating endometriosis.

Background: Endometriosis with bowel involvement is the most invasive form and can cause infertility, chronic pelvic pain and bowel symptoms. Effective surgical treatment of endometriosis requires complete excision of endometriosis and in same case may require segmental rectosigmoid resection.

Methods: Between December 1997 and October 2003, 55 patients with rectovaginal endometriosis underwent a combined laparoscopic vaginal technique.

Bridge-1 is expressed in human granulosa cells and is involved in the activin A signaling cascade.

The present study investigates the expression of the coactivator Bridge-1 in the human ovary and its role in activin A signaling in the human granulosa cell line HGL-5. Expression of Bridge-1 can be stimulated by activin A, an important factor for follicle maturation, matching the increase of Smad 2, 3, and 4; treatment with Bridge-1-small interfering RNA is decreasing not only the expression of Bridge-1 but also the expression of Smad2, 3, and 4 in HGL-5 cells.

The molecular signature of endometriosis-associated endometrioid ovarian cancer differs significantly from endometriosis-independent endometrioid ovarian cancer.

Objective: To determine whether endometriosis-associated endometrioid cancer (EAOC) is a specific entity compared with endometrioid cancer not associated with endometriosis (OC).

Design: Case-control study.

Setting: University hospital research laboratory.