Publications by authors named "C Balsano"

Article Synopsis
  • Metabolic dysfunction-associated steatotic fatty liver disease (MASLD) is a growing global health concern linked to liver disease, driven by factors like mitochondrial dysfunction, lipid metabolism issues, inflammation, and oxidative stress.
  • Changes in diet and lifestyle, particularly through natural compounds, can positively influence these mechanisms and promote better liver health by altering epigenetic factors and mitochondrial functions.
  • This review discusses recent research on how bioactive compounds affect mitochondria in the context of MASLD, aiming to improve our understanding and treatment of the disease through insights into epigenetic modifications.
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Artificial Intelligence (AI) has recently been shown as an excellent tool for the study of the liver; however, many obstacles still have to be overcome for the digitalization of real-world hepatology. The authors present an overview of the current state of the art on the use of innovative technologies in different areas (big data, translational hepatology, imaging, and transplant setting). In clinical practice, physicians must integrate a vast array of data modalities (medical history, clinical data, laboratory tests, imaging, and pathology slides) to achieve a diagnostic or therapeutic decision.

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Sarcopenia is a severe condition common to various chronic diseases and it is reckoned as a major health problem. It encompasses many different molecular mechanisms that have been for a while discovered but not definitely clarified. Although sarcopenia is a disability status that leads to serious health consequences, the scarcity of suitable animal models has curtailed research addressing this disorder.

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