Publications by authors named "C Balkman"
Objective: To evaluate the clinical benefit and adverse events following outpatient intravenous (IV) ketamine-lidocaine (KL) infusions for palliation of cancer pain in dogs and cats.
Methods: Medical records from 15 years (2008 to 2023) were searched and data reviewed retrospectively. Animals were prescribed ketamine (0.
Article Synopsis
- Canine oral squamous cell carcinoma (COSCC) is a common and aggressive oral tumor in dogs, with a significant risk of metastasis at diagnosis.
- The typical treatment involves wide surgical excision, which can have a considerable impact on a dog's quality of life.
- Recent research shows that the MEK inhibitor trametinib, an FDA-approved drug for human cancers, effectively reduces COSCC cell growth and may lead to tumor regression in some canine patients, offering new hope for better treatment options.
Case Summary: Minimally invasive surgery is an increasingly popular alternative to open surgery in veterinary medicine. Compared with traditional surgical approaches, laparoscopic pancreatectomy provides a less invasive approach and has several potential benefits, including improved visualization, reduced infection rate and decreased postoperative pain. Laparoscopic partial pancreatectomy has been described in humans, dogs and pigs but not cats.
View Article and Find Full Text PDFThe current feline genotyping array of 63 k single nucleotide polymorphisms has proven its utility for mapping within breeds, and its use has led to the identification of variants associated with Mendelian traits in purebred cats. However, compared to single gene disorders, association studies of complex diseases, especially with the inclusion of random bred cats with relatively low linkage disequilibrium, require a denser genotyping array and an increased sample size to provide statistically significant associations. Here, we undertook a multi-breed study of 1,122 cats, most of which were admitted and phenotyped for nine common complex feline diseases at the Cornell University Hospital for Animals.
View Article and Find Full Text PDFBackground: Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer in dogs. Despite this, relatively few reports of this disease exist pertaining to prognostic factors and outcome.
Aim: To evaluate factors associated with survival in dogs with all subtypes of HCC diagnosed on histopathology.