A Review of Orthodontic Considerations before and after Alveolar Bone Grafting in Patients with Cleft Lip and Palate.

There are many factors to consider regarding the orthodontic treatment of an individual with cleft lip and palate in relation to the alveolar bone graft procedure. Some of these are: the sequence and timing of treatment, indications for pre-graft orthodontics, the appropriate appliances that should be used, and considerations in post-graft orthodontics. A review of some of the current concepts, management, and protocols are described.

Host-microbe computational proteomic landscape in oral cancer revealed key functional and metabolic pathways between Fusobacterium nucleatum and cancer progression.

Oral squamous cell carcinoma (OSCC) is the most common manifestation of oral cancer. It has been proposed that periodontal pathogens contribute to OSCC progression, mainly by their virulence factors. However, the main periodontal pathogen and its mechanism to modulate OSCC cells remains not fully understood.

Projecting the Population Level Burden of CKD Progression According to Urine Albumin-to-Creatinine Ratio Categories.

Introduction: Urinary albumin-to-creatinine ratio (uACR) is an independent predictor of chronic kidney disease (CKD) progression. However there is limited evidence on the burden of CKD according to uACR categories at the population level. This study estimates future clinical and financial burden of CKD according to uACR categories using the Inside CKD microsimulation.

Using Chronic Kidney Disease as a Model Framework to Estimate Healthcare-Related Environmental Impact.

Introduction: While the economic and clinical burden of chronic diseases are well documented, their environmental impact remains poorly understood. We developed a framework to estimate the environmental impact of a disease care pathway using chronic kidney disease (CKD) as an example.

Methods: A life cycle assessment framework was developed for the CKD care pathway and validated by experts.