Dietary and related data collected during pregnancy in the Avon Longitudinal Study of Parents and Children (ALSPAC).

The Avon Longitudinal Study of Parents and Children (ALSPAC) is a longitudinal birth cohort study based in the south-west of the UK. Pregnant women resident in and around the city of Bristol with expected delivery dates between 1 April 1991 and 31 December 1992 were invited to take part. The initial number of pregnancies enrolled was 14,541.

Management of diarrhoea in patients with stable ulcerative colitis with low FODMAP diet, amitriptyline, ondansetron or loperamide: the MODULATE RCT.

Background: Many patients with ulcerative colitis report ongoing diarrhoea even when their disease is stable and in remission.

Design: MODULATE was a pragmatic, multicentre, seamless, adaptive, phase 2/3 open-label, parallel-group, multiarm multistage randomised controlled trial.

Setting And Participants: People aged over 18 years with stable ulcerative colitis who had diarrhoea, recruited from secondary care sites in the United Kingdom.

Using a smartphone app to monitor Raynaud's attacks and quantify skin colour changes-towards objective outcome measures for Raynaud's.

Objectives: Our overall aim was to develop a smartphone app to collect photographic images of Raynaud's phenomenon (RP) attacks alongside patient reported outcome measures (PROMs). Specific objectives included assessing the feasibility of patients documenting RP attacks using mobile phones, developing image analysis methods to document colour change, and comparing photographic parameters to 'non-imaging' app and paper diary parameters.

Methods: Study 1: 36 patients with systemic sclerosis (SSc)-related RP photographed RP attacks over 15 days as well as completing an RP paper diary.

British Society of Gastroenterology practice guidance on the management of acute and chronic gastrointestinal symptoms and complications as a result of treatment for cancer.

Background: Survival rates after a diagnosis of cancer are improving. Poorly managed gastrointestinal (GI) side effects can interfere with delivery of curative cancer treatment. Long-term physical side effects of cancer therapy impinge on quality of life in up to 25% of those treated for cancer, and GI side effects are the most common and troublesome.

Seafood intake in children at age 7 years and neurodevelopmental outcomes in an observational cohort study (ALSPAC).

Purpose: Seafood is rich in other essential nutrients such as long-chain fatty acids, selenium and iodine that play an important role in neurodevelopment and cognitive function. The association between seafood intake in childhood and cognitive outcomes has not been well evidenced. Our aim was to investigate the association between seafood intake in children at age 7 years and cognitive and behavioural outcomes at age 7-9 years.