A 46-year-old man presented with progressive painful monocular vision loss and left leg paresthesias. Workup demonstrated multifocal demyelinating lesions and CSF-restricted oligoclonal bands. He was diagnosed with multiple sclerosis (MS), but follow-up testing was notable for positive myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG).
View Article and Find Full Text PDFEquine road transport is stressful and associated with an increased risk of behavioral problems, injuries, respiratory and gastrointestinal diseases. This cross-sectional survey-based study aimed to describe transport-related practices and the perception of behavioral and health issues in Germany. The survey targeted horse owners (amateurs and professionals) and obtained demographic details, the participant's experience, frequency and duration of transportation, and behavioral and health problems related to equine transportation.
View Article and Find Full Text PDFDementia (London)
February 2025
Background: In the UK, care home staff are often involved in musical practices as part of their professional activities. However, to date there is a lack of relational evidence that underpins improvisational music-making programmes in care homes, as related to the wellbeing of care home staff and musicians who deliver such work. This process evaluation accesses Manchester Camerata's 20-week 'Music in Mind Training' programme for care home staff working with people living with dementia in care homes, with a focus on care home staff.
View Article and Find Full Text PDFA 28-year-old Black woman presented with both typical and atypical features of multiple sclerosis in the setting of multimorbidity including psychiatric history, complicating diagnosis and treatment. This case illustrates the importance of differential diagnosis and longitudinal follow-up before committing to disease-modifying therapy. Individualized treatment decision-making is highlighted.
View Article and Find Full Text PDFWe present a case of myelitis in a 63-year-old woman with breast adenocarcinoma treated with pembrolizumab. MRI showed multiple T2-hyperintense lesions throughout the spinal cord, and CSF demonstrated lymphocytic pleocytosis. We discuss the differential diagnosis of myelitis in the setting of cancer and immune checkpoint inhibitors.
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