N-Butylpyrrolidinone is an equally good solvent as N,N-dimethylformamide for microwave assisted solid phase peptide synthesis.

Solid-phase peptide synthesis (SPPS) is the prevailing method for synthesizing research peptides today. However, SPPS is associated with a significant environmental concern due to the utilization of hazardous solvents such as N,N-dimethylformamide (DMF) or N-methylpyrrolidone, which generate substantial waste. In light of this, our research endeavors to identify more environmentally friendly solvents for SPPS.

Forty Years after the Discovery of Its Nucleolytic Activity: [Cu(phen) ] Shows Unattended DNA Cleavage Activity upon Fluorination.

[Cu(phen) ] (phen=1,10-phenanthroline) is the first and still one of the most efficient artificial nucleases. In general, when the phen ligand is modified, the nucleolytic activity of its Cu complex is significantly reduced. This is most likely due to higher steric bulk of such ligands and thus lower affinity to DNA.

Evaluation of physical euthanasia for neonatal piglets on-farm.

Twenty-seven neonate piglets (range from 0.35 to 1.17 kg) were evaluated for the effectiveness of blunt force trauma as a method of on-farm cull.

Interventional Angiography: Radiation Protection for the Examiner by using Lead-free Gloves.

Introduction: The radiation exposure to unprotected parts of the body requires special attention for the interventional radiologist. During angiographic procedures, hands are exposed to the direct X-ray beam and scattered radiation.

Aim: The aim of the study was to evaluate the radiation exposure of examiners hand with the use of lead-free X-ray protective gloves in clinical practice in terms of shielding and sense of touch.

Haemostasis with the FISH Vascular Closure Device after 6 French Transfemoral Accesses in Interventional Radiology: Clinical Results.

Introduction: Endovascular procedures have increased for different indications over the recent years. To achieve a safe haemostasis after arterial puncture and for more comfort for the patients different vascular closure devices have been developed.

Aim: To evaluate the effectiveness and safety of a percutaneous closure system based on a matrix patch for achieving haemostasis.