Parallel coupling of gas chromatography to mass spectrometry and solid deposition Fourier transform infrared spectroscopy: an innovative approach to address challenging identifications.

The request for novel hyphenated instruments and techniques, capable of affording exhaustive information and results, is a focus continuously watched out. In this context, the present work aimed at the development of an integrated system combining gas chromatographic (GC) separation with mass spectrometry (MS) and (solid deposition) Fourier transform infrared spectroscopy (FTIR) detection. An external transfer line was designed in the lab for the parallel coupling of the two detectors, in such a way to obtain complementary analytical information consisting of an MS spectrum, an IR spectrum and linear retention indices (LRI), within a single analysis.

Gas chromatographic techniques and spectroscopic approaches for a deep characterization of Piper gaudichaudianum Kunth essential oil from Brazil.

Piper gaudichaudianum Kunth essential oil (EO) is a natural source of bioactive components, having multiple therapeutic applications. Its chemical composition is highly variable, and strictly depends on abiotic factors, resulting in various biological activities. The present study details the utilization of multiple gas chromatographic techniques alongside nuclear magnetic resonance (NMR) spectroscopy to characterize the essential oil of Piper gaudichaudianum Kunth from Brazil.

The online coupling of liquid chromatography to Fourier transform infrared spectroscopy using a solute-deposition interface: A proof of concept.

Hyphenated techniques combining chromatographic and spectroscopic methods are the gold standard to effectively handle the emerging challenges in the analysis of unknown chemical components in mixtures, and in this regard the coupling of liquid chromatography to Fourier transform infrared spectroscopy (LC-FTIR) is no exception. While earlier attempts to couple LC to IR spectroscopy relied almost entirely on offline techniques, clear motivations for implementing online LC-FTIR instrumentation emerged from the need for shorter analysis time, a higher degree of automation and sample throughput, better reproducibility, and reduced contamination. Most recent designs of LC-FTIR concepts have aimed to combine the advantages of both approaches by means of a solvent-elimination interface.

Sacroplasty for local or massive localization of multiple myeloma.

The purpose of this study was to assess the efficacy of cementoplasty in the treatment of sacral multiple myelomas. We retrospectively reviewed the records of eight patients (four women and four men; age range 47-68 years; mean age 57.8) who underwent cementoplasty for painful osteolytic localization of multiple myeloma between April 2007 and May 2009.